I have now several times experienced a hard crash (game just closes) on loading saves after the program has been run for a while. This does not seem to be tied to which save-game is loaded at all, but rather seems to be some internal corruption in the engine. Seems to be new (not sure) in 353289 or 352881.
I do know this bug-report is about the least helpful possible, but it is all the information I can give you.
Load a game at the wrong moment. Seems to happen after the game engine was used for a few hours.