Mouse Moves left and can't click anything

do you have a controller plugged in that either has stick drift or the stick moved to the left?

No there was no controller and as u (should be) able to see the mouse stays at the same place on the monitor so it is something in the game

8 hours ago, Nike7nPlays said:

No there was no controller

The video above is what it looks like when a controller and a mouse are connected at the same time and controller is hitting a button. Wireless controller maybe?

There were several other cases like that with weird unexplained mouse movement

Spoiler

 

 

Could you please attach your DxDiag?