I suffocated 2 of my dupes. About half a day later I get a red pop-up message box that one of the dead dupes is lashing out to relieve stress, and has broken a building (she didn't, of course). The message also didn't go away until I quit and restarted the game.
Lock high decor requirement dupe(s) in a room, then let them starve for a couple of days. Then seal the room off so they suffocate in their own CO2 after they're really stressed.