UPDATE: Solved by removing other saving files in "my document" and reinstalling the game. I'm not sure if the saving will work for you.
When I played up to 418 days, the game crashed, and when I try to resume the saved game, the client just stuck and reported no response.
The saving is attached.
Version 211867, Platform: win10
Steps to Reproduce
When resume the saving above, the client crashed (OxygenNotIncluded.exe has no response).
This issue has not been confirmed by a developer yet.