Old saves cause a crash when Duplicants attempt to pick up certain items. This appears to be the case with most things made of Genetic Ooze.
This happens with no mods loaded.
Logfile and save attached. Run the save for a few seconds so the dupes can pick up the Muckroot to move to the ration box.
Load the provided save, unpause, then wait for one of the Duplicants to pick up the Muckroot.