I've experienced a repeated game crash. I figured it was something I was doing in game. I've narrowed it down to building a wire in a specific piece of granite. If I let the building progress as queued the game will crash. If I cancel the wire, build a tile then build a wire it is fine. I'm hoping this very specific crash can be useful to you.
Towards the bottom righthand part of my base I am building a spaceheater, when the wire directly under it gets touched by a dupe, the game will crash.