I can not play

most likely a client mod doing it 

but if that was the case game itself would simply just disable all the mods so if its about a mod you have a another mod that prevents game from disabling your mods 

go to steam> dst workshop>browse/subscribed items 

and delete the prevent disable mods mod in there it should work 

 

well if its not the mods 

go to library right click to the game 

properties>local files>verify integrity of game files 

and wait if it doesnt work im sorry i cant do anything else

The error in the background is saying the game is unable to write to the save folders. Please see this for instructions:
https://support.klei.com/hc/en-us/articles/360029882171-Getting-a-Unable-to-write-to-config-directory-Error-Message