Nothing game-breaking, but I have noticed that whenever a dupe gets the urge to go to the restroom (the toilet over their head), the notification "No restrooms have been built" shows up in the window for a second or two.
Also (I suppose this may be intended), when in combat, the status window of the creature says "Harvest pending" accompanied by the little harvest scythe symbol next to them.
#1. Happens literally every time a dupe gets the urge to go to the restroom. #2. Initiate combat with a creature.