Oxygen not included crashes on startup

I have the same problem which is occurred after new dlc release. I did everything like you but nothing change. The game still crushing on startup. Could someone help pls?

Same here, i even deleted my save games from document folder, removed all add ons, etc etc. pretty much new install

This game has some issue(s) with mod subscribing (this can be also steam issue or both)
Recently since more than year I decided to play again. I downloaded/started the game and it was crashing with error related to mod (*_legacy.bin something like that). I unsubscribed to ALL mods - it started to work. I subscribed to any mod - game crashed with error to UNINSTALLED at that moment mod. I asked some questions related to this on game official discord, so
That helped me:
1. Unsubscribe to all mods and close the STEAM.
2. Delete/Move folder C:\Users\Your_Profile_Name\Documents\Klei\OxygenNotIncluded
3. Start the STEAM and REcheck all game files.
After that everything was ok. I resubscribed to my mods and game was running fine.
There also suggested to install mod - Mod Updater which better update mods.
And clean the STEAM cache (STEAM -> Settings -> Downloads -> Clean Cache (button) ), but this not helped me
You may also try to read that topic. 

 

Edited July 21, 2024 by Anatory R

Yesterday I solved the problem by uninstalling and reinstalling the NVIDIA drivers.

I don't know if this helps, but I recommend reinstalling your graphics card drivers.

I hope this experience can help!