The question on everyones mind when it comes to the topic of Webber and the spider is how it happened, but I find the story of when it happened to be more interesting. In my time playing Webber, I've realized that a lot of his dialogue hints at important details to when he ended up in his situation. These hints however may not be entirely true.
It seems to be widely believed that Webber had been eaten by the spider after he had arrived in the world of Don't Starve, which is not a bad assumption by any means. It would make sense after all; Webber shortly dies after the incident and Wilson stumbles across his remains. As stated before, however, there is evidence from story elements and quotes from the characters that can prove this to be false.
Wickerbottoms ability to name the species of the Don't Starve world can supposedly give insight of what might exist in the real world, however, there is a contradiction to this. Despite being able to name the deerclops, her choice of words for quotes for the spider family shows signs of questioning, as if the information she has gathered is new. This would imply that the species of spiders in the Don't Starve world are not in the real world. This is only true if Wickerbottoms ability to name the species of the Don't Starve world truly give us knowledge of the real worlds creatures. More concrete evidence of my point is given by Webbers quotes related to Maxwell and quotes that reference his life before Don't Starve.
The way Webber refers to himself (or themselves) plays a key role in this evidence, as there are many quotes of his that give insight to his life before the incident. Some of these quotes include:
"Bucket-o-poop- I saw mum use this in her gardens."
"Fishing Rod- I miss grandpa's fishing trips."
"Cartographer's Desk- Heh heh. I was never allowed in father's study."
These quotes all seem to imply that he had a normal life of a child before he had become fused with the spider, and the afforementioned situation with Wickerbottom can prove that the spider was not in the real world, meaning that he couldn't have become "Webber" until he was within the Don't Starve world. However, in the same context of his life before, this quote proves otherwise:
"Pumpkin Lantern- Just like we used to make at home!"
Just like WE used to make at home. This implies that at some point in the real world, he had been eaten by the spider, making them into Webber. One could say that this might have been a mistake within the dialogue. After all, the dialogue for WX-78 is filled with contradictions to his abilities. However, there is even more evidence of this, some of which comes from how Webber had arrived in the world of Don't Starve.
When Webber examines Maxwells statue, he will say the following quote:
"That's the guy who said he could help us."
This is very similar to how Wilson was taken to the Don't Starve world, as he also told Wilson he could help. The important part of this quote is how Webber uses us instead of me.
These quotes may very well prove that the spiders from the Don't Starve world do exist in the real world, or at least where Webber had lived, and may also prove that Webber was Webber before he could be Webber; by going to the Don't Starve world. For the record, I was also thinking about this while waiting out summer on my Webber world.
This bothers me way more than it should.