This is less a bug report but more a pointer toward a solution: When you load a game the simulation is paused, this leads to the duplicants not following commands, the resources seem to be gone (as the simulation needs to run a bit to update the numbers) and one is unable to build (dito). The solution to all this is what I have posted in don't know how many bug reports so far and is simple: The game is paused, press space to continue...
Pending