After launching a small first rocket into space for this file I noticed that the rocket icon on the starmap is missing. The arrow indicating the destination is present, but there's no rocket and it isn't just graphical because clicking where the rocket should be doesn't do anything. The rocket must be sent home from the rocket control station inside the rocket since the destination menu can't be accessed from the starmap.
Not sure how to reproduce it, this is the first rocket I built on this save file. Everything leading up to launch was pretty normal (except a small door permission glitch that was easily resolved).
- Reloading seems to have fixed the issue entirely.