Version TU0211704. I was already in game and loaded my auto-save. I pressed "c" to start giving a 'cancel' order while the icons were still greyed out, and instead a tutorial style message popped up in the message log on the left saying "This message is a notification". Each press of "c" spawned a new one, with an increasing number "This message is a notification(1)". Clicking the message brought up a tutorial style dialog about duplicants needing access to areas you give them orders in, or something of that nature. Unfortunately, when I alt+tabbed to start the bug report, the behavior ceased. I am unable to reproduce it currently.
Steps to Reproduce
Load a save While the buttons are still all grayed out from the initial load, press "c"
This issue has not been confirmed by a developer yet.