It appears that door state change requests are not being saved.
Should be pretty easy to reproduce.
Steps to Reproduce
1. Create a door (in my case it's just a simple pneumatic door, I haven't tested with other doors) 2. Schedule a state change (open or lock) 3. Save the game 4. Reload it. You should see that the state change request is no longer there.
This issue has not been confirmed by a developer yet.