The new auto-disinfect mechanic needs to be revised. I have a large pool of polluted water with a granite foundation. The base is in contact with slime chunks and the Slimelung germs are migrating rapidly to the granite. Since the Dupes are now auto-disinfecting structures, they keep entering the polluted water to clean the infected tiles. This leads to worse health for the Dupes and a lot of wasted work for the little ones.
Build a granite tile structure near a slime chunk and watch the Dupes get crazy cleaning it constantly.